Ribose 1-dehydrogenase (NADP+)

In enzymology, ribose 1-dehydrogenase (NADP⁺) () is an enzyme that catalyzes the chemical reaction

The three substrates of this enzyme are D-ribose, oxidised nicotinamide adenine dinucleotide phosphate (NADP⁺), and water. Its products are D-ribonic acid, reduced NADPH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is D-ribose:NADP⁺ 1-oxidoreductase. Other names in common use include D-ribose dehydrogenase (NADP⁺), NADP⁺-pentose-dehydrogenase, and ribose 1-dehydrogenase (NADP⁺).

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