Ribitol 2-dehydrogenase

In enzymology, a ribitol 2-dehydrogenase () is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are ribitol and oxidised nicotinamide adenine dinucleotide (NAD⁺). Its products are D-ribulose, reduced NADH, and a proton.

This enzyme participates in pentose and glucuronate interconversions.

Nomenclature

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is ribitol:NAD⁺ 2-oxidoreductase. Other names in common use include adonitol dehydrogenase, ribitol dehydrogenase A (wild type), ribitol dehydrogenase B (mutant enzyme with different properties), and ribitol dehydrogenase D (mutant enzyme with different properties).

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