Rhamnogalacturonan rhamnohydrolase (, RG-rhamnohydrolase, RG alpha-L-rhamnopyranohydrolase) is an enzyme with systematic name rhamnogalacturonan oligosaccharide alpha-L-Rha-(1->4)-alpha-D-GalA rhamnohydrolase. This enzyme catalyses the following chemical reaction
The enzyme is part of the degradation system for rhamnogalacturonan I in Aspergillus aculeatus.