In enzymology, quinoline-4-carboxylate 2-oxidoreductase () is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are quinoline-4-carboxylic acid, an electron acceptor, and water. Its products are 2-hydroxycinchoninic acid and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating). Other names in common use include quinaldic acid 4-oxidoreductase, and quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating).