Pyridoxine 4-dehydrogenase

In enzymology, pyridoxine 4-dehydrogenase () is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are pyridoxine and oxidised nicotinamide adenine dinucleotide phosphate (NADP⁺). Its products are pyridoxal, reduced NADPH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donors with NAD⁺ or NADP⁺ as acceptors. The systematic name of this enzyme class is pyridoxine:NADP⁺ 4-oxidoreductase. Other names in common use include pyridoxin dehydrogenase, pyridoxol dehydrogenase, and pyridoxine dehydrogenase. This enzyme participates in vitamin B₆ metabolism.

References