Pseudotropine

Pseudotropine (3β-tropanol, ψ-tropine, 3-pseudotropanol, or PTO) is a derivative of tropane and an isomer of tropine. Pseudotropine can be found in the Coca plant along with several other alkaloids

Synthesis

In the laboratory it is made by the reduction of tropinone: According to the article, a good stereoselectivity of pseudotropine over endotropine could be achieved when employing a Meerwein–Ponndorf–Verley reduction or sodium metal in n-pentanol.

Derivatives

• Pudafensine
• Tropigline (Tigloidine, ticloidine) [533-08-4] (E)-form Produced by Physalis peruviana. Anticholinergic, anti parkinsonian drug.
• Convolamine
• Valtropine
• Pseudotropine benzoate (tropacocaine)

See also

• Pseudotropine acyltransferase
• Atropine
• Tropine
• Tropinone

References