Propargylamine is an organic compound with the formula HCâ¡CCH<sub>2</sub>NH<sub>2</sub>. It is a colorless, odorless liquid that is used as a precursor to other compounds. Propargyl amines are produced by reactions of amines with propargyl halides.
The behavior of propargyl amine is illustrated by its acylation benzoyl chloride to the amide. A Sonogashira coupling of the terminal alkyne end with another equivalent of benzoylchloride gives the dicarbonyl, a precursor to an oxazole.
Propargylamine is used in the synthesis of: