Pregnenolone 16α-carbonitrile

Pregnenolone 16α-carbonitrile (PCN) is a synthetic, steroidal antiglucocorticoid and pregnane X receptor agonist.

Synthesis

16-DPA is reacted with potassium cyanide to give a 68% crop of needles.

See also

• Pregnenolone
• Mifepristone
• Ketoconazole
• Dexamethasone

References