Phthalide is an organic chemical compound with the molecular formula C<sub>8</sub>H<sub>6</sub>O<sub>2</sub>. It is a white solid and the simplest benzo lactone. It is prepared from hydroxymethylbenzoic acid.
The phthalide core is found in a variety of more complex chemical compounds including dyes (such as phenolphthalein), fungicides (such as tetrachlorophthalide, often referred to simply as "phthalide"), and natural oils (such as butylphthalide).
5-bromophthalide [64169-34-2] is used in the synthesis of Roxadustat and Citalopram.
3-(4'-chlorophenyl)phthalide is a chemical that serves function in the synthesis of Setazindol & Chlortalidone.
Phthalide synthesis:
Phthalide has known uses in the synthesis of hydralazine, & pipethiadene.
Phthalide is used in the synthesis of dibenzosuberone.