1-(2-Phenylethyl)pyrrolidine (PEP) is a chemical compound of the phenethylamine family. It is an analogue of 2-phenylethylamine where the amine has been replaced by a pyrrolidine ring.
The ñ-methyl (i.e., amphetamine derivative is 1-(ñ-methylphenethyl)pyrrolidine (MPEP), the ò-keto derivative is phenacylpyrrolidine, and the combined ñ-methyl and ò-keto (i.e., cathinone) derivative is ñ-pyrrolidinopropiophenone (ñ-PPP). Prolintane is the ñ-propyl derivative of PEP.
PEP is the base chemical structure for a series of stimulant drugs, including:
All of these compounds differ from PEP in that the alpha carbon is extended and a ketone is attached to the beta carbon (with the exception of prolintane), among other modifications.
A cyclized phenethylamine and 2-aminoindane derivative is Pyr-AI ((2-indanyl)pyrrolidine). It is the analogue of 2-aminoindane (2-AI) in which the amine has been replaced with a pyrrolidine group. The drug has been described as having strong and long-lasting amphetamine-like effects in rodents.