Perillyl-alcohol dehydrogenase () is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are (-)-perillyl alcohol and oxidised nicotinamide adenine dinucleotide (NAD<sup>+</sup>). Its products are (-)-perillaldehyde, reduced NADH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is perillyl-alcohol:NAD<sup>+</sup> oxidoreductase. This enzyme is also called perillyl alcohol dehydrogenase. In Perilla frutescens, it is part of the pathway from the monoterpene, (S)-limonene to (âÂÂ)-perillaldehyde.