Methanol dehydrogenase (nicotinoprotein) (, NDMA-dependent methanol dehydrogenase, nicotinoprotein methanol dehydrogenase, methanol:N,N-dimethyl-4-nitrosoaniline oxidoreductase) is an enzyme with systematic name methanol:acceptor oxidoreductase. This enzyme catalyses the following chemical reaction
This enzyme contains Zn<sup>2+</sup> and Mg<sup>2+</sup>.