In enzymology, a manganese-transporting ATPase () is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are ATP, H<sub>2</sub>O, and Mn<sup>2+</sup>, whereas its 3 products are ADP, phosphate, and Mn<sup>2+</sup>.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is called ATP phosphohydrolase (manganese-importing). This enzyme is also known as ABC-type manganese permease complex.