The manetail snake eel (Ophichthus urolophus) is an eel in the family Ophichthidae (worm/snake eels). It was described by Coenraad Jacob Temminck and Hermann Schlegel in 1846, originally under the genus Conger. It is a marine, tropical eel which is known from the Indo-Pacific. It inhabits deep waters, but is found in muddy sediments in shallow waters on rare occasions. Males can reach a maximum total length of .
The manetail snake eel's diet consists of benthic invertebrates.