In enzymology, a lysineâÂÂtRNA ligase () is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are ATP, -lysine, and tRNA, whereas its 3 products are AMP, diphosphate, and -lysyl-tRNA.
This enzyme participates in 3 metabolic pathways: lysine biosynthesis, aminoacyl-trna biosynthesis, and amyotrophic lateral sclerosis (als).
This enzyme belongs to the family of ligases, to be specific, those forming carbonâÂÂoxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is -lysine:tRNA ligase (AMP-forming). Other names in common use include lysyl-tRNA synthetase, lysyl-transfer ribonucleate synthetase, lysyl-transfer RNA synthetase, -lysine-transfer RNA ligase, lysine-tRNA synthetase, and lysine translase.