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Long-chain-fatty-acid—luciferin-component ligase

In enzymology, a long-chain-fatty-acid—luciferin-component ligase () is an enzyme that catalyzes the chemical reaction

ATP + an acid + protein AMP + diphosphate + an acyl-protein thioester

The 3 substrates of this enzyme are ATP, acid, and protein, whereas its 3 products are AMP, diphosphate, and acyl-protein thioester.

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is long-chain-fatty-acid:protein ligase (AMP-forming). This enzyme is also called acyl-protein synthetase.

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