Leukotriene receptor

The leukotriene (LT) receptors are G protein-coupled receptors that bind and are activated by the leukotrienes. They include the following proteins:

• Leukotriene B4 receptors (BLTRs) – bind to and are activated by LTB4:
• BLT₁ (Leukotriene B₄ receptor 1) –
• BLT₂ (Leukotriene B₄ receptor 2) –
• Cysteinyl leukotriene receptors (CysLTRs) – bind to and are activated by LTC4, LTD4, and LTE4:
• CysLT₁ (Cysteinyl leukotriene receptor 1) –
• CysLT₂ (Cysteinyl leukotriene receptor 2) –

The recently elucidated CysLT_E, represented by GPR99/OXGR1, may constitute a third CysLTR.

See also

• Eicosanoid receptor
• Oxoeicosanoid receptor
• Prostaglandin receptor
• Thromboxane receptor

References

External links

• IUPHAR GPCR Database – Leukotriene receptors