Phospholipase C (EC 3.1.4.3, lipophosphodiesterase I, Clostridium welchii ñ-toxin, Clostridium oedematiens ò- and ó-toxins, lipophosphodiesterase C, phosphatidase C, heat-labile hemolysin, ñ-toxin) is an enzyme with systematic name phosphatidylcholine cholinephosphohydrolase. This enzyme catalyses the following chemical reaction
The bacterial enzyme is a zinc protein. It also acts on sphingomyelin and phosphatidylinositol.