In enzymology, an isopiperitenol dehydrogenase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are (-)-trans-isopiperitenol and NAD<sup>+</sup>, whereas its 3 products are (-)-isopiperitenone, NADH, and H<sup>+</sup>.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is (-)-trans-isopiperitenol:NAD<sup>+</sup> oxidoreductase. This enzyme participates in monoterpenoid biosynthesis.