The inferior orbital fissure is a gap between the greater wing of sphenoid bone, and the maxilla. It connects the orbit (anteriorly) with the infratemporal fossa and pterygopalatine fossa (posteriorly).
The medial end of the inferior orbital fissure diverges laterally from the medial end of the superior orbital fissure. It is situated between the lateral wall of the orbit and the floor of the orbit.
The fissure gives passage to multiple structures, including: