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Imiloxan

Imiloxan is a drug which is used in scientific research. It acts as a selective antagonist for the α<sub>2B</sub> adrenergic receptor, and has been useful for distinguishing the actions of the different α<sub>2</sub> adrenergic subtypes.

Synthesis

The imidazole portion of imiloxan is prepared by the reaction of an imidate with the diethyl acetal of aminoacetaldehyde. N-Alkylation of the imidazole with ethyl iodide gives imiloxan.

References

External links