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Heparin lyase

The enzyme heparin lyase () catalyzes the following process:

Eliminative cleavage of polysaccharides containing (1→4)-linked <small>D</small>-glucuronate or <small>L</small>-iduronate residues and (1→4)-α-linked 2-sulfoamino-2-deoxy-6-sulfo-<small>D</small>-glucose residues to give oligosaccharides with terminal 4-deoxy-α-<small>D</small>-gluc-4-enuronosyl groups at their non-reducing ends

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is heparin lyase. Other names in common use include heparin eliminase, and heparinase.

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