The enzyme guanosine-3â²,5â²-bis(diphosphate) 3â²-diphosphatase (EC 3.1.7.2) catalyzes the reaction.
This enzyme belongs to the family of hydrolases, specifically of those acting on diphosphoric monoester bonds. The systematic name is guanosine-3â²,5â²-bis(diphosphate) 3â²-diphosphohydrolase. Other names in common use include guanosine-3â²,5â²-bis(diphosphate) 3â²-pyrophosphatase, PpGpp-3'-pyrophosphohydrolase, and PpGpp phosphohydrolase. This enzyme participates in purine metabolism.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .