Glycerol-3-phosphate 2-O-acyltransferase (, sn-2-glycerol-3-phosphate O-acyltransferase, glycerol-3-phosphate O-acyltransferase) is an enzyme with systematic name acyl-CoA:sn-glycerol 3-phosphate 2-O-acyltransferase. This enzyme catalyses the following chemical reaction
This membrane-associated enzyme is required for suberin or cutin synthesis in plants.