Glutamate synthase (ferredoxin)

In enzymology, glutamate synthase (ferredoxin) () is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are L-glutamic acid and oxidised ferredoxin. Its products are L-glutamine, α-ketoglutaric acid, reduced ferredoxin, and two protons.

Classification

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH₂ group of donors with an iron-sulfur protein as acceptor.

Nomenclature

The systematic name of this enzyme class is L-glutamate:ferredoxin oxidoreductase (transaminating). Other names in common use include:

• ferredoxin-dependent glutamate synthase,
• ferredoxin-glutamate synthase,
• glutamate synthase (ferredoxin-dependent), and
• ferredoxin-glutamine oxoglutarate aminotransferase (Fd-GOGAT).

Biological role

This enzyme participates in nitrogen metabolism. It has 5 cofactors: flavin adenine dinucleotide, iron, sulfur, iron-sulfur, and flavoprotein.

See also

• Glutamate synthase (NADH)
• Glutamate synthase (NADPH)

References