In enzymology, glucoside 3-dehydrogenase () is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are sucrose and an electron acceptor. Its products are 3-ketosucrose and the corresponding reduced acceptor.
This enzyme participates in galactose metabolism and starch and sucrose metabolism. It employs one cofactor, FAD.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-aldohexoside:acceptor 3-oxidoreductase. Other names in common use include D-glucoside 3-dehydrogenase, D-aldohexopyranoside dehydrogenase, D-aldohexoside:cytochrome c oxidoreductase, D-glucoside 3-dehydrogenase, hexopyranoside-cytochrome c oxidoreductase, and D-aldohexoside:(acceptor) 3-oxidoreductase.