Glucose 1-dehydrogenase (NADP+)

In enzymology, glucose 1-dehydrogenase (NADP⁺) () is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are D-glucose and oxidised nicotinamide adenine dinucleotide phosphate (NADP⁺). Its products are glucono-δ-lactone, reduced NADPH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is D-glucose:NADP⁺ 1-oxidoreductase. Other names in common use include nicotinamide adenine dinucleotide phosphate-linked aldohexose, dehydrogenase, NADP⁺-linked aldohexose dehydrogenase, NADP⁺-dependent glucose dehydrogenase, and glucose 1-dehydrogenase (NADP⁺).

See also

• Glucose 1-dehydrogenase (NAD+) which catalyses the same reaction but uses an alternative cofactor.

References