The enzyme glucarate dehydratase () catalyzes the chemical reaction
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is <small>D</small>-glucarate hydro-lyase (5-dehydro-4-deoxy-<small>D</small>-glucarate-forming). Other names in common use include <small>D</small>-glucarate dehydratase, and <small>D</small>-glucarate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , and .