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Germacrene A hydroxylase

Germacrene A hydroxylase () is an enzyme with systematic name (+)-germacrene-A,NADPH:oxygen oxidoreductase (12-hydroxylating). This enzyme catalyses the following chemical reaction

(+)-germacrene A + NADPH + H<sup>+</sup> + O<sub>2</sub> germacra-1(10),4,11(13)-trien-12-ol + NADP<sup>+</sup> + H<sub>2</sub>O

Germacrene A hydroxylase is a heme-thiolate protein (P-450).

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