Fructose 5-dehydrogenase (NADP+)

In enzymology, fructose 5-dehydrogenase (NADP⁺) () is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are D-fructose (shown in its keto form) and oxidised nicotinamide adenine dinucleotide phosphate (NADP⁺). ts products are 5-dehydro-D-fructose, reduced NADPH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is D-fructose:NADP⁺ 5-oxidoreductase. Other names in common use include 5-ketofructose reductase (NADP⁺), 5-keto-D-fructose reductase (NADP⁺), fructose 5-(nicotinamide adenine dinucleotide phosphate), dehydrogenase, D-(-)fructose:(NADP⁺) 5-oxidoreductase, and fructose 5-dehydrogenase (NADP⁺).

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