In enzymology, a farnesol dehydrogenase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are 2-trans,6-trans-farnesol and NADP<sup>+</sup>, whereas its 3 products are 2-trans,6-trans-farnesal, NADPH, and H<sup>+</sup>.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is 2-trans,6-trans-farnesol:NADP<sup>+</sup> 1-oxidoreductase. Other names in common use include NADP<sup>+</sup>-farnesol dehydrogenase, and farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase.