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Di-tert-butylzinc

Di-tert-butylzinc is a compound with the formula ZnC<sub>8</sub>H<sub>18</sub>. This compound is used as a meta activating reagent in the syntheses of N,N-dimethyl-3-iodoaniline from N,N-dimethylaniline.

Synthesis

Di-tert-butylzinc is obtained from the reaction between tert-butyllithium and zinc chloride.

2 (CH<sub>3</sub>)<sub>3</sub>CLi + ZnCl<sub>2</sub> → Zn(C(CH<sub>3</sub>)<sub>3</sub>)<sub>2</sub> + 2 LiCl

References