De Los Santos, also spelled delos Santos in the Philippines, is a Spanish surname meaning "of the saints". Notable people with the surname include:
- Abel De Los Santos (born 1992), American baseball player
- Alejandro de los Santos (1902âÂÂ1982), Argentinian football player
- Alfredo de los Santos (disambiguation), multiple people
- Enyel De Los Santos (born 1995), Dominican Republic baseball player
- Epifanio de los Santos (1871âÂÂ1928), Filipino historian
- Fautino de los Santos (born 1986), Dominican Republic baseball player
- Gonzalo de los Santos (born 1976), Uruguayan football player
- Jaime de los Santos (born 1946), Filipino general
- Ramón de los Santos (1949âÂÂ2015), Dominican Republic baseball player
- Valerio de los Santos (born 1972), Dominican Republic baseball player
- William de los Santos, (born 1964), actor
- Yerry De Los Santos (born 1997), Dominican baseball player
- Luis de los Santos (first baseman), Dominican baseball player
- Luis De Los Santos (third baseman), Dominican baseball player
See also