In enzymology, a dTDP-galactose 6-dehydrogenase () is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are dTDP-D-galactose, NADP<sup>+</sup>, and H<sub>2</sub>O, whereas its 3 products are dTDP-D-galacturonate, NADPH, and H<sup>+</sup>.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is dTDP-D-galactose:NADP<sup>+</sup> 6-oxidoreductase. This enzyme is also called thymidine-diphosphate-galactose dehydrogenase. This enzyme participates in nucleotide sugars metabolism.