DTDP-6-deoxy-L-talose 4-dehydrogenase (NAD<sup>+</sup>) (, tll (gene name)) is an enzyme with systematic name dTDP-6-deoxy-beta-L-talose:NAD<sup>+</sup> 4-oxidoreductase. This enzyme catalyses the following chemical reaction
The enzyme from bacterium Aggregatibacter actinomycetemcomitans participates in the biosynthesis of the serotype c-specific polysaccharide antigen.