In enzymology, coniferyl-alcohol dehydrogenase () is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are coniferyl alcohol and oxidised nicotinamide adenine dinucleotide phosphate (NADP<sup>+</sup>). Its products are coniferyl aldehyde, reduced NADPH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The systematic name of this enzyme class is coniferyl-alcohol:NADP<sup>+</sup> oxidoreductase. This enzyme is also called CAD.