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Chondroitin B lyase

The enzyme chondroitin B lyase () catalyzes the following process:

Eliminative cleavage of dermatan sulfate containing (1→4)-β-<small>D</small>-hexosaminyl and (1→3)-β-<small>D</small>-glucurosonyl or (1→3)-α-<small>L</small>-iduronosyl linkages to disaccharides containing 4-deoxy-β-<small>D</small>-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (ΔUA-GalNAc-4S).

Glossary:

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is chondroitin B lyase. Other names in common use include chondroitinase B, ChonB, and ChnB.

References