In enzymology, a chenodeoxycholoyltaurine hydrolase () is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are chenodeoxycholoyltaurine and H<sub>2</sub>O, whereas its two products are chenodeoxycholate and taurine.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is chenodeoxycholoyltaurine amidohydrolase. This enzyme participates in bile acid biosynthesis.