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Benzoylhydrazine

Benzoylhydrazine, also known as benzenecarbohydrazide, or benzoic hydrazide is an organic chemical compound, which is a hydrazide functionally linked to benzoic acid. It is typically used as a precursor in pharmaceutical and chemical synthesis, or used as a chemical intermediate for the production of hydrazine-based products.

Metabolism

During metabolism it forms metabolites including hydrazine, benzoic acid and hippuric acid.

Safety

It is both neurotoxic and hepatoxic as well as an osteolathyrogen and carcinogen, and also a potential teratogen that affects the development of fetal abnormalities.

The mechanism responsible for the development of osteolathyrism is identical to the reference osteolathyrogen β-aminopropionitrile.

A violent reaction occurs with benzeneselenic acid. When heated to decomposition it emits toxic fumes of nitrogen oxides.

References