In enzymology, an aspartateâÂÂammonia ligase (ADP-forming) () is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are ATP, L-aspartate, and NH<sub>3</sub>, whereas its 3 products are ADP, phosphate, and L-asparagine.
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ligases (amide synthases). The systematic name of this enzyme class is L-aspartate:ammonia ligase (ADP-forming). Other names in common use include asparagine synthetase (ADP-forming), and asparagine synthetase (adenosine diphosphate-forming). This enzyme participates in nitrogen metabolism.