In enzymology, an aryl-aldehyde dehydrogenase (NADP+) () is an enzyme that catalyzes the chemical reaction
The 5 substrates of this enzyme are aromatic aldehyde, NADP<sup>+</sup>, AMP, diphosphate, and H<sub>2</sub>O, whereas its 4 products are aromatic acid, NADPH, H<sup>+</sup>, and ATP.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is aryl-aldehyde:NADP+ oxidoreductase (ATP-forming). Other names in common use include aromatic acid reductase, and aryl-aldehyde dehydrogenase (NADP+).