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Arsenate reductase (glutaredoxin)

Arsenate reductase (glutaredoxin) () is an enzyme that catalyzes the chemical reaction

arsenate + glutaredoxin arsenite + glutaredoxin disulfide + H<sub>2</sub>O

Thus, the two substrates of this enzyme are arsenate and glutaredoxin, whereas its 3 products are arsenite, glutaredoxin disulfide, and water.

This enzyme belongs to the family of oxidoreductases, specifically those acting on phosphorus or arsenic in donor with disulfide as acceptor. The systematic name of this enzyme class is glutaredoxin:arsenate oxidoreductase.

Structural studies

As of late 2007, 12 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , , , , and .

References