Anditomin is an oxygenated meroterpenoid produced by Aspergillus stellatus or Aspergillus variecolor.
Aspergillus variecolor produces anditomin from 3,5-dimethylorsellinic acid and farnesyl pyrophosphate using 12 enzymes. The enzyme AndA firstly dehydrogenates one ring of preandiloid B to make preaniloid C. Next it causes a complex ring isomerisation to make anditomin.
Anditomin can dissolve in ethyl acetate or chloroform. Anditomin forms tetragonal crystals with space group P4<sub>1</sub> (No. 76), with unit cell dimensions a = 9.310 and c = 24.84 à, and unit cell volume = 2153 à<sub>3</sub> with Z = 4, and density = 1.27 gcm<sup>âÂÂ3</sup>.