ñ<sub>5</sub>ò<sub>1</sub>, also known as the fibronectin receptor, is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. It is composed of ñ<sub>5</sub> (ITGA5/CD49e) and ò<sub>1</sub> (ITGB1/CD29) subunits. It is the primary receptor for fibronectin. The interaction of VLA-5 with fibronectin plays an important role in regulating inflammatory cytokine production by human articular chondrocytes (From the Cell Migration Gateway ITGA5 ITGB1).
ñ<sub>5</sub>ò<sub>1</sub>-integrin is transported inside the cell by the kinesin KIF1C, a kinesin-3 organelle transporter that walks along microtubules.