Alanopine dehydrogenase () is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are alanopine, oxidised nicotinamide adenine dinucleotide (NAD<sup>+</sup>) and water. Its products are L-alanine, reduced NADH, pyruvic acid, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2,2'-iminodipropanoate:NAD+ oxidoreductase (L-alanine-forming). Other names in common use include ALPDH, alanopine[meso-N-(1-carboxyethyl)-alanine]dehydrogenase, meso-N-(1-carboxyethyl)-alanine:NAD+ oxidoreductase, alanopine: NAD+ oxidoreductase, ADH, and alanopine:NAD+ oxidoreductase.