Zeaxanthin epoxidase (, Zea-epoxidase) is an enzyme with systematic name zeaxanthin,NAD(P)H:oxygen oxidoreductase. This enzyme catalyses the following chemical reaction
zeaxanthin + 2 NAD(P)H + 2 H<sup>+</sup> + 2 O<sub>2</sub> violaxanthin + 2 NAD(P)<sup>+</sup> + 2 H<sub>2</sub>O (overall reaction)
(1a) zeaxanthin + NAD(P)H + H<sup>+</sup> + O<sub>2</sub> antheraxanthin + NAD(P)<sup>+</sup> + H<sub>2</sub>O
(1b) antheraxanthin + NAD(P)H + H<sup>+</sup> + O<sub>2</sub> violaxanthin + NAD(P)<sup>+</sup> + H<sub>2</sub>O
Zeaxanthin epoxidase is a flavoprotein (FAD) that is active under conditions of low light.
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