Zapata County Independent School District is a public school district based in Zapata, Texas, United States. The district's boundaries parallel that of Zapata County.
In 2019, the school district received a B from the Texas Education Agency. In 2017, the Texas Education Agency gave the school district an accountability rating of "met standard."
In 2017, the Texas Education Agency gave the school district a rating of 74 in college readiness, compared to a target score of 60.