ZC-B, also known as 3-(4-bromo-2,5-dimethoxyphenyl)azetidine or as 2C-B-AZET, is a phenethylamine derivative which acts as a serotonin receptor agonist selective for the 5-HT<sub>2</sub> subtypes, with an EC<sub>50</sub> of 1.6nM at 5-HT<sub>2A</sub>, vs 5.8nM at 5-HT<sub>2C</sub>. It is structurally related to the psychedelic phenethylamines 2C-B and DOB, but with the amine side chain conformationally restricted as an azetidine ring.