Yitzhaki () is a Hebrew surname. Notable people with the surname include:
See also
- Abraham Yizhaki, a 16th-century Greek writer, Talmudic scholar and dayyan
- Shlomo Yitzchaki, known as Rashi (c.âÂÂ1040âÂÂ1105), a French rabbi
- Meir Itzhaki, a former Israeli footballer
- Tal Itzhaki (born 1956), an Israeli theatre designer and translator