Yaakov Yitzchok Ezrachi (; born August 1933) is a Rosh Yeshiva (dean) at the Mir Yeshiva in Jerusalem.
Ezrachi was born in Jerusalem to Yisrael Ezrachi and Hinda. His mother was the daughter of Baruch Shlom, a graduate of the Knesses Yisrael Yeshiva in Slobodka who served as a rabbi in South Africa and was the grandson of Uri David Apiryon, rabbi of à ½agaràin Lithuania and author of the book Apiryon David. He studied at the Mir Yeshiva.
Since 1979, he has served as one of the rosh yeshivas of the Mir Yeshiva, next to Eliezer Yehuda Finkel.
In 2024, Ezrachi travelled to Buenos Aires, Argentina, to speak about the Torah to an audience of seven thousand.
Ezrachi was married to Rivka, a daughter of Chaim Leib Shmuelevitz, also a former Rosh Yeshiva at the Mirrer Yeshiva. Rivka died in 2019.
Ezrachi's brother was Baruch Mordechai Ezrachi, another prominent Haredi rabbi.